Stuff We’re Doing

New for 2023: UC Merced Developmental Biology and Neurobiology labs are holding joint lab meetings and journal clubs. Looking forward to learning something new and making new collaborations. Thanks Xuecai Ge for organizing!

The UC Merced Neuro labs go to SFN! Ramen Saha (036.04/D6) Nov 12 1-5pm for nBAF and IEGs, Eva Cai (107.09/A8) Nov 13 8-noon for Hh signaling in cilia, Cal Larnerd (150.06/OO5) Nov 13 8-noon for EtOH tolerance memories, Xiaoliang Liu (606.24/C56) Nov 16 8-noon for Numb promoting Hh signaling, and Brian Wang (728.28/HH11) Nov 16 1-5pm for sex-specific thirsty water seeking pathways!

Fred Wolf was elected Chair of the Quantitative and Systems Biology Graduate Group at UC Merced. Learn more here.

Chris Amemiya is co-organizing the joint meeting of the Pan-American Society for Evolutionary Developmental Biology and the Society for Developmental Biology, in Vancouver BC, July 17-22, 2022. Abstracts are due April 11. Learn more here.

Stephanie Woo is co-organizer for the Virtual Gastrulation Zoom Talks seminar series. Register here and visit Twitter for updates.


	

Recent Funding

Stephanie Woo recently received an NSF CAREER award for the “Contact inhibition of locomotion as a positioning mechanism during endoderm morphogenesis.” Read more here. Congratulations Stephanie!

Stephanie Woo recently received an NIH R21 award for the “Determining the role of cellular forces in endoderm differentiation and development.” Read more here. Congratulations Stephanie!

Ramen Saha recently received an NIH R21 award for the “BAF complex inhibitors in neuronal development and functions.” Read more here. Congratulations Ramen!

Xuecai Ge recently received an NIH R01 award for the “Regulation of the Hedgehog Pathway by new cilium proteins in Development and Disease.” Read more here. Congratulations Susan!

Xuecai Ge recently received an NSF CAREER award for “Mechanistic Studies of Cilium Proteins in Cell Signaling.” Read more here. Congratulations Susan!

Fred Wolf recently received an R21/R33 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) for “Engram encoding for ethanol tolerance in Drosophila.” Read more here. Congratulations Fred!

Michael Cleary recently received an R21 from the National Institute of Neurological Disorders and Stroke (NINDS) for “Transfer RNA Dynamics During Neural Differentiation.” Read more here. Congratulations Mike!

Fred Wolf recently received an R21 from National Institute on Alcohol Abuse and Alcoholism (NIAAA) for “Presynaptic structure and function in ethanol tolerance development.” Read more here. Congratulations Fred!

Recent Publications

Papers published by our groups in 2021 and 2022

It was an exciting publishing 2 years for the Developmental Biology and Neurobiology groups at UC Merced.

The Cleary lab published “mRNAs encoding neurodevelopmental regulators have equal N6-methyladenosine stoichiometry in Drosophila neuroblasts and neurons” in Neural Development. You can find the work of graduate student Josephine Sami at https://doi.org/10.1186/s13064-022-00166-4

The Ge lab published “A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction” in Nature Structural & Molecular Biology. You can find the work of graduate student Jingyi Zhang at https://doi.org/10.1038/s41594-022-00838-z

The Oviedo lab published “Non-traditional roles of immune cells in regeneration: an evolutionary perspective” in Development. You can find the work of graduate students Beryl Arinda and Yacoub Innabi at https://doi.org/10.1242/dev.199903

The Oviedo lab published “Direct Current Electric Stimulation Alters the Frequency and the Distribution of Mitotic Cells in Planarians” in Bioelectricity. You can find the work of graduate students Devon Davidian and Benjamin Ziman at https://doi.org/10.1089/bioe.2020.0026

The Oviedo lab published “Restoration of DNA Integrity and Cell Cycle by Electric Stimulation in Planarian Tissues Damaged by Ionizing Radiation” in bioRxiv. You can find the work of graduate students Devon Davidian, Melanie LeGro, Paul Barghouth, Salvador Rojas, Benjamin Ziman, Eli Maciel at https://www.biorxiv.org/content/10.1101/2021.05.16.444365v1

The Wolf lab published “Thirst interneurons that promote water seeking and limit feeding behavior in Drosophila” in eLife. You can find the work of graduate students Dan Landayan and Brian Wang, and research tech Jennifer Zhou at https://doi.org/10.7554/elife.66286

The Ge lab published “Myomegalin regulates Hedgehog pathway by controlling PDE4D at the centrosome” in Molecular Biology of the Cell. You can find the work of graduate students Hualing Peng, Jingyi Zhang, Amanda Ya, and Sammy Villa at https://doi.org/10.1091/mbc.e21-02-0064

The Woo lab published “Light-Induced GFP Expression in Zebrafish Embryos using the Optogenetic TAEL/C120 System” in Journal of Visualized Experiments. You can find the work of graduate student Jesselynn LaBelle at https://doi.org/10.3791/62818

The Amemiya lab published “Colloidal structure and proton conductivity of the gel within the electrosensory organs of cartilaginous fishes” in iScience. You can find the work of graduate student Molly Phillips and others at https://doi.org/10.1016/j.isci.2021.102947

The Cleary lab published “Progenitor-derived ribosomal RNA supports protein synthesis in Drosophila neurons” in Natural Sciences. You can find the work of graduate students Jade Fee and Mohamed Aboukilila at https://doi.org/10.1002/ntls.20210032

The Ge lab published “Control of the Hedgehog pathway by compartmentalized PKA in the primary cilium” in Science China Life Sciences. You can find this review at https://doi.org/10.1007/s11427-021-1975-9