Stefan Materna

We focus on a few specific cell types that, once specified, execute distinct morphogenetic programs to assemble embryonic tissues such as the embryonic gut, early blood vasculature, and Kupffer’s vesicle, which is involved in left/right axis formation. How do only a few lineage-specific transcription factors regulate a complex program that guides cells to physically assemble into complex tissues? This ties into the more general question how other events in development, that also require the precise control of hundreds of genes, are orchestrated.

The Materna Lab